Comprehensive transcriptional profiling of prion infection in mouse models reveals networks of responsive genes

<p>Abstract</p> <p>Background</p> <p>Prion infection results in progressive neurodegeneration of the central nervous system invariably resulting in death. The pathological effects of prion diseases in the brain are morphologically well defined, such as gliosis, vacuolat...

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Bibliographic Details
Main Authors: Robertson Catherine, Phillipson Clark, Parchaliuk Debra, Medina Sarah, Sorensen Garrett, Booth Stephanie A
Format: Article
Language:English
Published: BMC 2008-03-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/9/114