PKC-dependent human monocyte adhesion requires AMPK and Syk activation.

PKC plays a pivotal role in mediating monocyte adhesion; however, the underlying mechanisms of PKC-mediated cell adhesion are still unclear. In this study, we elucidated the signaling network of phorbol ester PMA-stimulated human monocyte adhesion. Our results with pharmacological inhibitors suggest...

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Bibliographic Details
Main Authors: Mei-Ying Chang, Duen-Yi Huang, Feng-Ming Ho, Kuo-Chin Huang, Wan-Wan Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3405105?pdf=render