Transcriptional activation of low-density lipoprotein receptor gene by DJ-1 and effect of DJ-1 on cholesterol homeostasis.

Transcriptional activation of low-density lipoprotein receptor gene by DJ-1 and effect of DJ-1 on cholesterol homeostasis.

DJ-1 is a novel oncogene and also causative gene for familial Parkinson's disease park7. DJ-1 has multiple functions that include transcriptional regulation, anti-oxidative reaction and chaperone and mitochondrial regulation. For transcriptional regulation, DJ-1 acts as a coactivator that binds...

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Main Authors: Shiori Yamaguchi, Takuya Yamane, Kazuko Takahashi-Niki, Izumi Kato, Takeshi Niki, Matthew S Goldberg, Jie Shen, Kenji Ishimoto, Takefumi Doi, Sanae M M Iguchi-Ariga, Hiroyoshi Ariga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3364227?pdf=render

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http://europepmc.org/articles/PMC3364227?pdf=render

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