Aurora Kinase B Regulates Telomerase Activity via a Centromeric RNA in Stem Cells

Non-coding RNAs can modulate histone modifications that, at the same time, affect transcript expression levels. Here, we dissect such a network in mouse embryonic stem cells (ESCs). It regulates the activity of the reverse transcriptase telomerase, which synthesizes telomeric repeats at the chromoso...

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Bibliographic Details
Main Authors: Jan-Philipp Mallm, Karsten Rippe
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715005276