Design and evaluation of nano-hydroxyapatite/poly(vinyl alcohol) hydrogels coated with poly(lactic-co-glycolic acid)/nano-hydroxyapatite/poly(vinyl alcohol) scaffolds for cartilage repair

Abstract Background Poly(vinyl alcohol) (PVA) hydrogels have been widely used in synthetic cartilage materials. However, limitations of PVA hydrogels such as poor biomechanics and limited cell ingrowth remain challenges in this field. Methods This work aimed to design novel nano-hydroxyapatite (nano...

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Bibliographic Details
Main Authors: Weiping Su, Yihe Hu, Min Zeng, Mingqing Li, Shaoru Lin, Yangying Zhou, Jie Xie
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-019-1450-0