Convergence of Scaffold-Guided Bone Reconstruction and Surgical Vascularization Strategies—A Quest for Regenerative Matching Axial Vascularization

The prevalent challenge facing tissue engineering today is the lack of adequate vascularization to support the growth, function, and viability of tissue engineered constructs (TECs) that require blood vessel supply. The research and clinical community rely on the increasing knowledge of angiogenic a...

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Bibliographic Details
Main Authors: David S. Sparks, Flavia Medeiros Savi, Siamak Saifzadeh, Michael A. Schuetz, Michael Wagels, Dietmar W. Hutmacher
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00448/full