Reduced expression of the polymeric immunoglobulin receptor in pancreatic and periampullary adenocarcinoma signifies tumour progression and poor prognosis.

Reduced expression of the polymeric immunoglobulin receptor in pancreatic and periampullary adenocarcinoma signifies tumour progression and poor prognosis.

The polymeric immunoglobulin receptor (pIgR) is a key component of the mucosal immune system that mediates epithelial transcytosis of immunoglobulins. High pIgR expression has been reported to correlate with a less aggressive tumour phenotype and an improved prognosis in several human cancer types....

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Bibliographic Details
Main Authors: Richard Fristedt, Jacob Elebro, Alexander Gaber, Liv Jonsson, Margareta Heby, Yulyana Yudina, Björn Nodin, Mathias Uhlén, Jakob Eberhard, Karin Jirström
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4232506?pdf=render

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http://europepmc.org/articles/PMC4232506?pdf=render

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