Diagnostic accuracy of a loop-mediated isothermal PCR assay for detection of Orientia tsutsugamushi during acute Scrub Typhus infection.

There is an urgent need to develop rapid and accurate point-of-care (POC) technologies for acute scrub typhus diagnosis in low-resource, primary health care settings to guide clinical therapy.In this study we present the clinical evaluation of loop-mediated isothermal PCR assay (LAMP) in the context...

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Main Authors: Daniel H Paris, Stuart D Blacksell, Pruksa Nawtaisong, Kemajittra Jenjaroen, Achara Teeraratkul, Wirongrong Chierakul, Vanaporn Wuthiekanun, Pacharee Kantipong, Nicholas P J Day
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3172190?pdf=render