A single siRNA suppresses fatal encephalitis induced by two different flaviviruses.

Japanese encephalitis virus (JEV) and West Nile virus (WNV) are neurotropic flaviviruses that can cause acute encephalitis with a high fatality rate. Currently there is no effective treatment for these infections.We tested RNA interference (RNAi)-based intervention to suppress lethal JE and WN encep...

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Bibliographic Details
Main Authors: Priti Kumar, Sang Kyung Lee, Premlata Shankar, N Manjunath
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-04-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC1361782?pdf=render