The functions of Mediator in Candida albicans support a role in shaping species-specific gene expression.

The Mediator complex is an essential co-regulator of RNA polymerase II that is conserved throughout eukaryotes. Here we present the first study of Mediator in the pathogenic fungus Candida albicans. We focused on the Middle domain subunit Med31, the Head domain subunit Med20, and Srb9/Med13 from the...

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Bibliographic Details
Main Authors: Nathalie Uwamahoro, Yue Qu, Branka Jelicic, Tricia L Lo, Cecile Beaurepaire, Farkad Bantun, Tara Quenault, Peter R Boag, Georg Ramm, Judy Callaghan, Traude H Beilharz, André Nantel, Anton Y Peleg, Ana Traven
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3320594?pdf=render