Taiwanin E Induces Cell Cycle Arrest and Apoptosis in Arecoline/4-NQO-Induced Oral Cancer Cells Through Modulation of the ERK Signaling Pathway

Taiwanin E is a bioactive compound extracted from Taiwania cryptomerioides Hayata. In this research endeavor, we studied the anti-cancer effect of Taiwanin E against arecoline and 4-nitroquinoline-1-oxide-induced oral squamous cancer cells (OSCC), and elucidated the underlying intricacies. OSCC were...

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Main Authors: Shih-Hao Wang, Hsi-Chin Wu, Khan Farheen Badrealam, Yueh-Hsiung Kuo, Yun-Peng Chao, Hsi-Hsien Hsu, Da-Tian Bau, Vijaya Padma Viswanadha, Yi-Hui Chen, Pei-Jei Lio, Chung-Jen Chiang, Chih-Yang Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01309/full