Vitamin D induction of the human antimicrobial Peptide cathelicidin in the urinary bladder.

The urinary tract is frequently being exposed to potential pathogens and rapid defence mechanisms are therefore needed. Cathelicidin, a human antimicrobial peptide is expressed and secreted by bladder epithelial cells and protects the urinary tract from infection. Here we show that vitamin D can ind...

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Bibliographic Details
Main Authors: Olof Hertting, Åsa Holm, Petra Lüthje, Hanna Brauner, Robert Dyrdak, Aino Fianu Jonasson, Peter Wiklund, Milan Chromek, Annelie Brauner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3001888?pdf=render