Chronic loss of melanin-concentrating hormone affects motivational aspects of feeding in the rat.

Current epidemic obesity levels apply great medical and financial pressure to the strenuous economy of obesity-prone cultures, and neuropeptides involved in body weight regulation are regarded as attractive targets for a possible treatment of obesity in humans. The lateral hypothalamus and the nucle...

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Main Authors: Joram D Mul, Susanne E la Fleur, Pim W Toonen, Anthonieke Afrasiab-Middelman, Rob Binnekade, Dustin Schetters, Michel M M Verheij, Robert M Sears, Judith R Homberg, Anton N M Schoffelmeer, Roger A H Adan, Ralph J DiLeone, Taco J De Vries, Edwin Cuppen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3088702?pdf=render