Subnormothermic Machine Perfusion of Steatotic Livers Results in Increased Energy Charge at the Cost of Anti-Oxidant Capacity Compared to Normothermic Perfusion

Subnormothermic Machine Perfusion of Steatotic Livers Results in Increased Energy Charge at the Cost of Anti-Oxidant Capacity Compared to Normothermic Perfusion

There continues to be significant debate regarding the most effective mode of ex situ machine perfusion of livers for transplantation. Subnormothermic (SNMP) and normothermic machine perfusion (NMP) are two methods with different benefits. We examined the metabolomic profiles of discarded steatotic...

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Bibliographic Details
Main Authors: Negin Karimian, Siavash Raigani, Viola Huang, Sonal Nagpal, Ehab O. A. Hafiz, Irene Beijert, Paria Mahboub, Robert J. Porte, Korkut Uygun, Martin Yarmush, Heidi Yeh
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Metabolites
Subjects:
steatosis
subnormothermic
normothermic
machine perfusion
anti-oxidant
metabolomics
liver transplantation
Online Access:https://www.mdpi.com/2218-1989/9/11/246

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https://www.mdpi.com/2218-1989/9/11/246

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