When WAS Gene Diagnosis Is Needed: Seeking Clues Through Comparison Between Patients With Wiskott-Aldrich Syndrome and Idiopathic Thrombocytopenic Purpura

When WAS Gene Diagnosis Is Needed: Seeking Clues Through Comparison Between Patients With Wiskott-Aldrich Syndrome and Idiopathic Thrombocytopenic Purpura

Background: Wiskott-Aldrich syndrome (WAS) is a rare and severe X-linked disorder with variable clinical phenotypes correlating with the type of mutations in the WAS gene. The syndrome is difficult to differentiate from idiopathic thrombocytopenic purpura (ITP) before genetic diagnosis. We retrospec...

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Bibliographic Details
Main Authors: Ying-Ying Jin, Jing Wu, Tong-Xin Chen, Ji Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
Wiskott-Aldrich syndrome
idiopathic thrombocytopenic purpura
primary immunodeficiency
gene mutation
hematopoietic stem cell transplantation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01549/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.01549/full

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