The Functional Versatility of Transferrin Receptor 2 and Its Therapeutic Value

Iron homeostasis is a tightly regulated process in all living organisms because this metal is essential for cellular metabolism, but could be extremely toxic when present in excess. In mammals, there is a complex pathway devoted to iron regulation, whose key protein is hepcidin (Hepc), which is a po...

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Bibliographic Details
Main Authors: Antonella Roetto, Mariarosa Mezzanotte, Rosa Maria Pellegrino
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Pharmaceuticals
Subjects:
SNC
Online Access:https://www.mdpi.com/1424-8247/11/4/115