Towards precision medicine: defining and characterizing adipose tissue dysfunction to identify early immunometabolic risk in symptom-free adults from the GEMM family study

Towards precision medicine: defining and characterizing adipose tissue dysfunction to identify early immunometabolic risk in symptom-free adults from the GEMM family study

Interactions between macrophages and adipocytes are early molecular factors influencing adipose tissue (AT) dysfunction, resulting in high leptin, low adiponectin circulating levels and low-grade metaflammation, leading to insulin resistance (IR) with increased cardiovascular risk. We report the cha...

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Bibliographic Details
Main Authors: Ernesto Rodriguez-Ayala, Esther C. Gallegos-Cabrales, Laura Gonzalez-Lopez, Hugo A. Laviada-Molina, Rocio A. Salinas-Osornio, Edna J. Nava-Gonzalez, Irene Leal-Berumen, Claudia Escudero-Lourdes, Fabiola Escalante-Araiza, Fatima A. Buenfil-Rello, Vanessa-Giselle Peschard, Antonio Laviada-Nagel, Eliud Silva, Rosa A. Veloz-Garza, Angelica Martinez-Hernandez, Francisco M. Barajas-Olmos, Fernanda Molina-Segui, Lucia Gonzalez-Ramirez, Rebeca Espadas-Olivera, Ricardo Lopez-Muñoz, Ruy D. Arjona-Villicaña, Victor M. Hernandez-Escalante, Martha E. Rodriguez-Arellano, Janeth F. Gaytan-Saucedo, Zoila Vaquera, Monica Acebo-Martinez, Judith Cornejo-Barrera, Huertas-Quintero Jancy Andrea, Juan Carlos Castillo-Pineda, Areli Murillo-Ramirez, Sara P. Diaz-Tena, Benigno Figueroa-Nuñez, Melesio E. Valencia-Rendon, Rafael Garzon-Zamora, Juan Manuel Viveros-Paredes, José Ángeles-Chimal, Jesús Santa-Olalla Tapia, José M. Remes-Troche, Salvador B. Valdovinos-Chavez, Eira E. Huerta-Avila, Juan Carlos Lopez-Alvarenga, Anthony G Comuzzie, Karin Haack, Xianlin Han, Lorena Orozco, Susan Weintraub, Jack W. Kent, Shelley A. Cole, Raul A. Bastarrachea
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Adipocyte
Subjects:
adipose tissue dysfunction
immunometabolism
postprandial tissue biopsies
non-coding micrornas
shotgun lipidomics
Online Access:http://dx.doi.org/10.1080/21623945.2020.1743116

Internet

http://dx.doi.org/10.1080/21623945.2020.1743116

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