LRG1 promotes proliferation and inhibits apoptosis in colorectal cancer cells via RUNX1 activation.

Leucine-rich-alpha-2-glycoprotein 1 (LRG1) has been shown to be involved in various human malignancies. Whether it plays a role in colorectal cancer (CRC) development remains unclear. Here, we investigated whether and through what mechanism LRG1 functions in human CRC cells. The plasma level of LRG1...

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Bibliographic Details
Main Authors: Ying Zhou, Xintian Zhang, Jingjing Zhang, Jingyuan Fang, Zhizheng Ge, Xiaobo Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5380360?pdf=render