The role of NK cells and CD39 in the immunological control of tumor metastases

Tumor metastases are responsible for death in the majority of cancer patients. Here we have explored the role of the ectonucleotidase CD39 in select models of tumor metastases and further tested the therapeutic anticancer activity of the NTPDase inhibitor sodium polyoxotungstate (POM-1). CD39 was ex...

Full description

Bibliographic Details
Main Authors: Haiyan Zhang, Dipti Vijayan, Xian-Yang Li, Simon C. Robson, Nishamol Geetha, Michele W. L. Teng, Mark J. Smyth
Format: Article
Language:English
Published: Taylor & Francis Group 2019-06-01
Series:OncoImmunology
Subjects:
nk
Online Access:http://dx.doi.org/10.1080/2162402X.2019.1593809