HDAC6, A Novel Cargo for Autophagic Clearance of Stress Granules, Mediates the Repression of the Type I Interferon Response During Coxsackievirus A16 Infection

HDAC6, A Novel Cargo for Autophagic Clearance of Stress Granules, Mediates the Repression of the Type I Interferon Response During Coxsackievirus A16 Infection

Autophagic cargoes ensure selective autophagy for the recognition and removal of various cytosolic aggregated proteins, damaged organelles, or pathogens. Stress granules (SGs), as antiviral immune complexes, serve a positive role in the type I interferon (IFN) response and can be targeted by autopha...

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Bibliographic Details
Main Authors: Yingcheng Zheng, Guoguo Zhu, Yinglian Tang, Jun Yan, Song Han, Jun Yin, Biwen Peng, Xiaohua He, Wanhong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Microbiology
Subjects:
autophagy
stress granule
HDAC6
coxsackievirus A16
type I interferon response
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00078/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.00078/full

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