Levobupivacaine inhibits proliferation and promotes apoptosis of breast cancer cells by suppressing the PI3K/Akt/mTOR signalling pathway

Levobupivacaine inhibits proliferation and promotes apoptosis of breast cancer cells by suppressing the PI3K/Akt/mTOR signalling pathway

Abstract Objective This study aimed to test the hypothesis that levobupivacaine has anti-tumour effects on breast cancer cells. Results Colony formation and transwell assay were used to determine breast cancer cells proliferation. Flow Cytometry (annexin V and PI staining) was used to investigate br...

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Bibliographic Details
Main Authors: Akosua Kotaa Kwakye, Sylvanus Kampo, Jiaxin Lv, Muhammad Noman Ramzan, Seidu A. Richard, Aglais Arredondo Falagán, Jerry Agudogo, Evans Atito-Narh, Qiu Yan, Qing-Ping Wen
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Research Notes
Subjects:
Levobupivacaine
Proliferation
Invasion
Apoptosis
Breast cancer
Online Access:http://link.springer.com/article/10.1186/s13104-020-05191-2

Internet

http://link.springer.com/article/10.1186/s13104-020-05191-2

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