TP63 basal cells are indispensable during endoderm differentiation into proximal airway cells on acellular lung scaffolds

Abstract The use of decellularized whole-organ scaffolds for bioengineering of organs is a promising avenue to circumvent the shortage of donor organs for transplantation. However, recellularization of acellular scaffolds from multicellular organs like the lung with a variety of different cell types...

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Bibliographic Details
Main Authors: Claudia Bilodeau, Sharareh Shojaie, Olivia Goltsis, Jinxia Wang, Daochun Luo, Cameron Ackerley, Ian M Rogers, Brian Cox, Martin Post
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-021-00124-4