Hidrox<sup>®</sup> Counteracts Cyclophosphamide-Induced Male Infertility through NRF2 Pathways in a Mouse Model

Hidrox<sup>®</sup> Counteracts Cyclophosphamide-Induced Male Infertility through NRF2 Pathways in a Mouse Model

Background: Every year, men use cyclophosphamide to treat various cancers and autoimmune diseases. On the one hand, this chemotherapy often has the beneficial effect of regressing the tumor, but on the other hand, it leads to infertility due to excessive oxidative stress and apoptosis in the testes...

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Bibliographic Details
Main Authors: Roberta Fusco, Angela Trovato Salinaro, Rosalba Siracusa, Ramona D’Amico, Daniela Impellizzeri, Maria Scuto, Maria Laura Ontario, Roberto Crea, Marika Cordaro, Salvatore Cuzzocrea, Rosanna Di Paola, Vittorio Calabrese
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Antioxidants
Subjects:
Nrf2
oxidative stress
inflammation
cyclophosphamide
Online Access:https://www.mdpi.com/2076-3921/10/5/778

Internet

https://www.mdpi.com/2076-3921/10/5/778

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