Anti-Inflammatory Effect of Emodin via Attenuation of NLRP3 Inflammasome Activation

Anti-Inflammatory Effect of Emodin via Attenuation of NLRP3 Inflammasome Activation

Emodin, an active constituent of oriental herbs, is widely used to treat allergy, inflammation, and other symptoms. This study provides the scientific basis for the anti-inflammasome effects of emodin on both in vitro and in vivo experimental models. Bone marrow-derived macrophages were used to st...

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Bibliographic Details
Main Authors: Ji-Won Han, Do-Wan Shim, Woo-Young Shin, Kang-Hyuk Heo, Su-Bin Kwak, Eun-Jeong Sim, Jae-Hyun Jeong, Tae-Bong Kang, Kwang-Ho Lee
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:International Journal of Molecular Sciences
Subjects:
emodin
interleukin (IL)-1β
NLRP3 inflammasome
sepsis
Online Access:http://www.mdpi.com/1422-0067/16/4/8102

Internet

http://www.mdpi.com/1422-0067/16/4/8102

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