Codelivery of DOX and siRNA by folate-biotin-quaternized starch nanoparticles for promoting synergistic suppression of human lung cancer cells

Codelivery of DOX and siRNA by folate-biotin-quaternized starch nanoparticles for promoting synergistic suppression of human lung cancer cells

In this paper, the self-assembled folate-biotin-quaternized starch nanoparticles (FBqS NPs) were used as carrier system of doxorubicin (DOX) and siRNAIGF1R for the codelivery of both into human lung adenocarcinoma cell lines (A549 cells) in vitro. The cytotoxicity, targeted ligand competition, cell...

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Bibliographic Details
Main Authors: Liangping Li, Suoju He, Lizhen Yu, Ezzat H Elshazly, Hui Wang, Kuanmin Chen, Song Zhang, Lixia Ke, Renmin Gong
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Drug Delivery
Subjects:
folate-biotin-quaternized starch nanoparticle
doxorubicin
sirna
codelivery
human lung cancer cell lines
Online Access:http://dx.doi.org/10.1080/10717544.2019.1606363

Internet

http://dx.doi.org/10.1080/10717544.2019.1606363

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