In vitro and in vivo immunomodulatory properties of octyl-β-d-galactofuranoside during Leishmania donovani infection

In vitro and in vivo immunomodulatory properties of octyl-β-d-galactofuranoside during Leishmania donovani infection

Abstract Background The chemotherapeutic arsenal available to treat visceral leishmaniasis is currently limited, in view of many drawbacks such as high cost, toxicity or emerging resistance. New therapeutic strategies are particularly needed to improve the management and the outcome in immunosuppres...

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Bibliographic Details
Main Authors: Hélène Guegan, Kevin Ory, Sorya Belaz, Aurélien Jan, Sarah Dion, Laurent Legentil, Christelle Manuel, Loïc Lemiègre, Thomas Vives, Vincent Ferrières, Jean-Pierre Gangneux, Florence Robert-Gangneux
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Parasites & Vectors
Subjects:
Visceral leishmaniasis
Leishmania donovani
Immunostimulation treatment
Galactofuranose
Furanoside
Macrophage polarization
Online Access:https://doi.org/10.1186/s13071-019-3858-0

Internet

https://doi.org/10.1186/s13071-019-3858-0

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