Application of Trio-Whole Exome Sequencing in Genetic Diagnosis and Therapy in Chinese Children With Epilepsy

Application of Trio-Whole Exome Sequencing in Genetic Diagnosis and Therapy in Chinese Children With Epilepsy

Epilepsy is one of the most common neurological disorders in pediatric patients with other underlying neurological defects. Identifying the underlying etiology is crucial for better management of the disorder. We performed trio-whole exome sequencing in 221 pediatric patients with epilepsy. Probands...

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Bibliographic Details
Main Authors: Tiejia Jiang, Jia Gao, Lihua Jiang, Lu Xu, Congying Zhao, Xiaojun Su, Yaping Shen, Weiyue Gu, Xiaohong Kong, Ying Yang, Feng Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Molecular Neuroscience
Subjects:
epilepsy
seizure
whole-exome sequencing
copy number variation sequencing
genetic diagnosis
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2021.699574/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2021.699574/full

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