Epididymal epithelium propels early sexual transmission of Zika virus in the absence of interferon signaling

Zika virus can be sexually transmitted. Here, Pletnev et al. show in an immunocompromised mouse model that the epithelial cells of the epididymis, rather than cells of the testis, vas deferens, prostate, or seminal vesicles, are the most likely source of male-to-female sexually transmitted ZIKV geno...

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Bibliographic Details
Main Authors: Alexander G. Pletnev, Olga A. Maximova, Guangping Liu, Heather Kenney, Bianca M. Nagata, Tatiana Zagorodnyaya, Ian Moore, Konstantin Chumakov, Konstantin A. Tsetsarkin
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22729-5