Role of Sterylglucosidase 1 (Sgl1) on the pathogenicity of Cryptococcus neoformans: potential applications for vaccine development

Role of Sterylglucosidase 1 (Sgl1) on the pathogenicity of Cryptococcus neoformans: potential applications for vaccine development

Cryptococcosis caused by C. neoformans and C. gattii affects a large population and is a cause of significant morbidity and mortality. Despite its public health burden, there are currently no vaccines against cryptococcosis and new strategies against such infections are needed. In this study, we dem...

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Bibliographic Details
Main Authors: Antonella eRella, Visesato eMor, Amir M. Farnoud, Ashutosh eSingh, Achraf A. Shamseddine, Elitza eIvanova, Nicholas eCarpino, Maria Teresa eMontagna, Chiara eLuberto, Maurizio eDel Poeta
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Microbiology
Subjects:
Gene Expression
Immunosuppression
glycolipid
vaccine development
Yeast genetics
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00836/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00836/full

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