APC and chromosome instability in colorectal cancer

Colon cancer is a common disease that can be sporadic or familial. An inactivated adenomatous polyposis coli (APC) suppressor gene is found in over 80% of colorectal tumors, this being an early alteration in the development of adenomatous polyps. APC function is not only critical for tumor initiatio...

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Bibliographic Details
Main Authors: C. M. Cabrera, M. A. López-Nevot
Format: Article
Language:English
Published: Aran Ediciones
Series:Revista Espanola de Enfermedades Digestivas
Subjects:
APC
Online Access:http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082005001000006&lng=en&tlng=en