RET mutated C-cells proliferate more rapidly than non-mutated neoplastic cells

A statistically significant higher prevalence of the RET p.Met918Thr somatic mutation, identified by direct sequencing, was previously reported in MTC > 2 cm than in smaller tumors. Aim of this study was to correlate the full RET and RAS mutation profile, identified by a Next Generation Sequencin...

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Bibliographic Details
Main Authors: Cristina Romei, Teresa Ramone, Chiara Mulè, Alessandro Prete, Virginia Cappagli, Loredana Lorusso, Liborio Torregrossa, Fulvio Basolo, Raffaele Ciampi, Rossella Elisei
Format: Article
Language:English
Published: Bioscientifica 2021-03-01
Series:Endocrine Connections
Subjects:
ret
ras
Online Access:https://ec.bioscientifica.com/view/journals/ec/10/2/EC-20-0589.xml