Proteomic profiling of the monothiol glutaredoxin Grx3 reveals its global role in the regulation of iron dependent processes.

Iron is an essential nutrient required as a cofactor for many biological processes. As a fungal commensal-pathogen of humans, Candida albicans encounters a range of bioavailable iron levels in the human host and maintains homeostasis with a conserved regulatory circuit. How C. albicans senses and re...

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Bibliographic Details
Main Authors: Selma S Alkafeef, Shelley Lane, Clinton Yu, Tingting Zhou, Norma V Solis, Scott G Filler, Lan Huang, Haoping Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-06-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008881