Gut Microbial Dysbiosis Is Associated With Profibrotic Factors in Liver Fibrosis Mice

Background and Aims: Continuous development will evolve into end-stage liver disease. Profibrotic factors NOX4 and RhoA participate in the activation of HSC and accelerate the development of liver fibrosis. Abnormal intrahepatic metabolism during liver fibrosis interferes with intestinal homeostasis...

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Bibliographic Details
Main Authors: Sizhe Wan, Yuan Nie, Yue Zhang, Chenkai Huang, Xuan Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.00018/full