Gut Microbial Dysbiosis Is Associated With Profibrotic Factors in Liver Fibrosis Mice
Background and Aims: Continuous development will evolve into end-stage liver disease. Profibrotic factors NOX4 and RhoA participate in the activation of HSC and accelerate the development of liver fibrosis. Abnormal intrahepatic metabolism during liver fibrosis interferes with intestinal homeostasis...
Main Authors: | Sizhe Wan, Yuan Nie, Yue Zhang, Chenkai Huang, Xuan Zhu |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-01-01
|
Series: | Frontiers in Cellular and Infection Microbiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fcimb.2020.00018/full |
Similar Items
-
Ursolic Acid Improves Intestinal Damage and Bacterial Dysbiosis in Liver Fibrosis Mice
by: Si-Zhe Wan, et al.
Published: (2019-11-01) -
Interaction Mechanisms Between the NOX4/ROS and RhoA/ROCK1 Signaling Pathways as New Anti- fibrosis Targets of Ursolic Acid in Hepatic Stellate Cells
by: Chenkai Huang, et al.
Published: (2019-05-01) -
Ursolic acid improves the bacterial community mapping of the intestinal tract in liver fibrosis mice
by: Sizhe Wan, et al.
Published: (2020-04-01) -
Interplay of Matrix Stiffness and c-SRC in Hepatic Fibrosis.
by: Jan eGörtzen, et al.
Published: (2015-12-01) -
Research progress in role of RhoA in onset and development of hepatic fibrosis
by: HONG Jinni
Published: (2013-08-01)