Enhancing post-expansion chondrogenic potential of costochondral cells in self-assembled neocartilage.

The insufficient healing capacity of articular cartilage necessitates mechanically functional biologic tissue replacements. Using cells to form biomimetic cartilage implants is met with the challenges of cell scarcity and donor site morbidity, requiring expanded cells that possess the ability to gen...

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Bibliographic Details
Main Authors: Meghan K Murphy, Daniel J Huey, Andrew J Reimer, Jerry C Hu, Kyriacos A Athanasiou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3578801?pdf=render