Effects of early- and mid-life stress on DNA methylation of genes associated with subclinical cardiovascular disease and cognitive impairment: a systematic review

Effects of early- and mid-life stress on DNA methylation of genes associated with subclinical cardiovascular disease and cognitive impairment: a systematic review

Abstract Background Traditional and novel risk factors cannot sufficiently explain the differential susceptibility to cardiovascular disease (CVD). Epigenetics may serve to partially explain this residual disparity, with life course stressors shown to modify methylation of genes implicated in variou...

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Bibliographic Details
Main Authors: Elena M. Vidrascu, Alexander C. Bashore, Timothy D. Howard, Justin B. Moore
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Medical Genetics
Subjects:
Cardiovascular disease
Cognitive impairment
DNA methylation
Early-life stress
Epigenetics
Mid-life stress
Online Access:http://link.springer.com/article/10.1186/s12881-019-0764-4

Internet

http://link.springer.com/article/10.1186/s12881-019-0764-4

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