Potent Effects of Flavonoid-Rich Extract from Rosa laevigata Michx Fruit against Hydrogen Peroxide-Induced Damage in PC12 Cells via Attenuation of Oxidative Stress, Inflammation and Apoptosis

Oxidative stress-induced neuronal death has an important role in the pathogenesis of neurodegenerative disorders. The effects and mechanisms of action of the total flavonoids (TFs) from Rosa laevigata Michx fruit against hydrogen peroxide (H2O2)-induced oxidative injury in PC12 cells were investigat...

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Bibliographic Details
Main Authors: Min Liu, Youwei Xu, Xu Han, Chen Liang, Lianhong Yin, Lina Xu, Yan Qi, Yanyan Zhao, Jinyong Peng, Changkai Sun
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/19/8/11816