Evolution of robustness and cellular stochasticity of gene expression.

Gene expression varies widely in cells with the same genotype and environment. Predicting the patterns of stochastic cellular fluctuations remains an unsolved challenge. I propose that the degree to which varying cellular components combine to determine robust phenotypes may predict the amount of va...

Full description

Bibliographic Details
Main Author: Steven A Frank
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3678995?pdf=render