Integrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers

Integrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers

Abstract The correspondence of cell state changes in diseased organs to peripheral protein signatures is currently unknown. Here, we generated and integrated single‐cell transcriptomic and proteomic data from multiple large pulmonary fibrosis patient cohorts. Integration of 233,638 single‐cell trans...

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Bibliographic Details
Main Authors: Christoph H Mayr, Lukas M Simon, Gabriela Leuschner, Meshal Ansari, Janine Schniering, Philipp E Geyer, Ilias Angelidis, Maximilian Strunz, Pawandeep Singh, Nikolaus Kneidinger, Frank Reichenberger, Edith Silbernagel, Stephan Böhm, Heiko Adler, Michael Lindner, Britta Maurer, Anne Hilgendorff, Antje Prasse, Jürgen Behr, Matthias Mann, Oliver Eickelberg, Fabian J Theis, Herbert B Schiller
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:EMBO Molecular Medicine
Subjects:
biomarker
data integration
fibrosis
proteomics
single‐cell RNA‐seq
Online Access:https://doi.org/10.15252/emmm.202012871

Internet

https://doi.org/10.15252/emmm.202012871

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