Advancing a MEMS-Based 3D Cell Culture System for in vitro Neuro-Electrophysiological Recordings

In this work we present advances in three dimensional (3D) neuronal cell culture systems based on a reversible assembly of a microbioreactor with a microelectrode array (MEA) to create a MEMS-based 3D cell culture system for in vitro neuro-electrophysiological recordings. A batch of six molds were m...

Full description

Bibliographic Details
Main Authors: Alex J. Bastiaens, Jean-Philippe Frimat, Teun van Nunen, Bart Schurink, Erik F. G. A. Homburg, Regina Luttge
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Mechanical Engineering
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmech.2018.00021/full