Rewiring carbon metabolism in yeast for high level production of aromatic chemicals
Microbial production of aromatic amino acid (AAA)-derived chemicals remains an outstanding metabolic engineering challenge. Here, the authors engineer baker’s yeast for high levels p-coumaric acid production by rewiring the central carbon metabolism and channeling more flux to the AAA biosynthetic p...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-10-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-12961-5 |