The potential of rapalogs to enhance resilience against SARS-CoV-2 infection and reduce the severity of COVID-19

Summary: COVID-19 disproportionately affects older people, with likelihood of severe complications and death mirroring that of other age-associated diseases. Inhibition of the mechanistic target of rapamycin complex 1 (mTORC1) has been shown to delay or reverse many age-related phenotypes, including...

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Bibliographic Details
Main Authors: Evelyne Bischof, MD, Richard C Siow, PhD, Alex Zhavoronkov, PhD, Matt Kaeberlein, ProfPhD
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:The Lancet. Healthy Longevity
Online Access:http://www.sciencedirect.com/science/article/pii/S2666756820300684