Pharmacodynamic analysis of hypertension caused by lenvatinib using real‐world postmarketing surveillance data

Abstract Lenvatinib is a tyrosine kinase inhibitor of the vascular endothelial growth factor receptor used against nonoperative thyroid cancer; however, hypertension is a major dose‐limiting side effect. In this study, hypertension caused by lenvatinib was described through a novel population pharma...

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Bibliographic Details
Main Authors: Yuki Otani, Hidefumi Kasai, Yusuke Tanigawara
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.12587