DNA methyltransferases are required to induce heterochromatic re-replication in Arabidopsis.
The relationship between epigenetic marks on chromatin and the regulation of DNA replication is poorly understood. Mutations of the H3K27 methyltransferase genes, Arabidopsis trithorax-related protein5 (ATXR5) and ATXR6, result in re-replication (repeated origin firing within the same cell cycle). H...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-07-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC3390372?pdf=render |