DNA methyltransferases are required to induce heterochromatic re-replication in Arabidopsis.

The relationship between epigenetic marks on chromatin and the regulation of DNA replication is poorly understood. Mutations of the H3K27 methyltransferase genes, Arabidopsis trithorax-related protein5 (ATXR5) and ATXR6, result in re-replication (repeated origin firing within the same cell cycle). H...

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Bibliographic Details
Main Authors: Hume Stroud, Christopher J Hale, Suhua Feng, Elena Caro, Yannick Jacob, Scott D Michaels, Steven E Jacobsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3390372?pdf=render