Comparison of Genetic and Self-Identified Ancestry in Modeling Intracerebral Hemorrhage Risk

Comparison of Genetic and Self-Identified Ancestry in Modeling Intracerebral Hemorrhage Risk

Background: We sought to determine whether a small pool of ancestry-informative DNA markers (AIMs) improves modeling of intracerebral hemorrhage (ICH) risk in heterogeneous populations, compared with self-identified race/ethnicity (SIRE) alone.Methods: We genotyped 15 preselected AIMs to perform pri...

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Bibliographic Details
Main Authors: Sandro Marini, Umme K. Lena, Katherine M. Crawford, Charles J. Moomaw, Fernando D. Testai, Steven J. Kittner, Michael L. James, Daniel Woo, Carl D. Langefeld, Jonathan Rosand, Christopher D. Anderson
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Neurology
Subjects:
genetics population
precision medicine
vascular diseases
risk factors
genetics
intracranial hemorrhage
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00514/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2018.00514/full

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