Characterization of gross genome rearrangements in Deinococcus radiodurans recA mutants

Abstract Genome stability in radioresistant bacterium Deinococcus radiodurans depends on RecA, the main bacterial recombinase. Without RecA, gross genome rearrangements occur during repair of DNA double-strand breaks. Long repeated (insertion) sequences have been identified as hot spots for ectopic...

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Bibliographic Details
Main Authors: Jelena Repar, Davor Zahradka, Ivan Sović, Ksenija Zahradka
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89173-9