GlyT1 Inhibitor NFPS Exerts Neuroprotection via GlyR Alpha1 Subunit in the Rat Model of Transient Focal Cerebral Ischaemia and Reperfusion

GlyT1 Inhibitor NFPS Exerts Neuroprotection via GlyR Alpha1 Subunit in the Rat Model of Transient Focal Cerebral Ischaemia and Reperfusion

Background/Aims: Glycine is a strychnine-sensitive inhibitory neurotransmitter in the central nervous system (CNS), especially in the spinal cord, brainstem, and retina. The objective of the present study was to investigate the potential neuroprotective effects of GlyT1 inhibitor N [3-(4'-fluor...

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Bibliographic Details
Main Authors: Baosheng Huang, Qingsong Xie, Xiaocheng Lu, Tengda Qian, Shuai Li, Ronglan Zhu, Wan Yu, Gong Chen, Zheng Chen, Xinlong Xu, Tianlu Wang, Lixin Li
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Glycine
NFPS
Salicylate
GlyR ɑ1
Ischaemia
Online Access:http://www.karger.com/Article/FullText/445556

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http://www.karger.com/Article/FullText/445556

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