Trehalose protects against oxidative stress by regulating the Keap1–Nrf2 and autophagy pathways

Trehalose protects against oxidative stress by regulating the Keap1–Nrf2 and autophagy pathways

Dysfunction of autophagy, which regulates cellular homeostasis by degrading organelles and proteins, is associated with pathogenesis of various diseases such as cancer, neurodegeneration and metabolic disease. Trehalose, a naturally occurring nontoxic disaccharide found in plants, insects, microorga...

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Bibliographic Details
Main Authors: Yuhei Mizunoe, Masaki Kobayashi, Yuka Sudo, Shukoh Watanabe, Hiromine Yasukawa, Daiki Natori, Ayana Hoshino, Arisa Negishi, Naoyuki Okita, Masaaki Komatsu, Yoshikazu Higami
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Redox Biology
Subjects:
Trehalose
Oxidative stress
p62
Autophagy
Keap1–Nrf2 system
Antioxidant
Online Access:http://www.sciencedirect.com/science/article/pii/S221323171730544X

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http://www.sciencedirect.com/science/article/pii/S221323171730544X

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