4.4 Å Resolution Cryo-EM structure of human mTOR Complex 1
ABSTRACT Mechanistic target of rapamycin (mTOR) complex 1 (mTORC1) integrates signals from growth factors, cellular energy levels, stress and amino acids to control cell growth and proliferation through regulating translation, autophagy and metabolism. Here we determined the cryo-electron microscopy...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SpringerOpen
2016-12-01
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Series: | Protein & Cell |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1007/s13238-016-0346-6 |