Genome Wide Methylome Alterations in Lung Cancer.

Genome Wide Methylome Alterations in Lung Cancer.

Aberrant cytosine 5-methylation underlies many deregulated elements of cancer. Among paired non-small cell lung cancers (NSCLC), we sought to profile DNA 5-methyl-cytosine features which may underlie genome-wide deregulation. In one of the more dense interrogations of the methylome, we sampled 1.2 m...

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Bibliographic Details
Main Authors: Nandita Mullapudi, Bin Ye, Masako Suzuki, Melissa Fazzari, Weiguo Han, Miao K Shi, Gaby Marquardt, Juan Lin, Tao Wang, Steven Keller, Changcheng Zhu, Joseph D Locker, Simon D Spivack
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4684329?pdf=render

Internet

http://europepmc.org/articles/PMC4684329?pdf=render

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